A researcher in Germany has proposed a novel unifying theory that may explain the molecular origin of rosacea in terms of climate adaptation. He contends that the new concept may not only explain why the disorder’s known triggers can cause flare-ups, but is also consistent with known therapeutic activity against rosacea’s signs and symptoms.

Genetics have long been thought to play a role in rosacea, but researchers have yet to isolate their influence. In one of the first studies of rosacea to measure and define genetic and environmental contributions, Dr. Daniel Popkin, assistant professor of dermatology at Case Western Reserve University, and colleagues have found that genetics and environmental factors may contribute equally to the disorder.

Although rosacea's connection to the cardiovascular system has been widely suggested ­– flushing and the potential development of visible blood vessels are two of the skin disorder's primary symptoms – recent studies point toward a potential broader connection between rosacea and cardiovascular disease.

A new study has documented for the first time the clinical differences between subtype 1 (erythematotelangiectatic) rosacea – characterized by facial redness and, sometimes, visible blood vessels – and a condition with visible blood vessels from sun damage known as telangiectatic photoaging (TP), providing a clear picture of the differences between the two disorders and aiding in appropriate treatment.¹

In a recent study funded by the National Rosacea Society, Dr. Yoshikazu Uchida, research dermatologist at the University of California – San Francisco, and colleagues overcame a challenge that may lead to important advances in the treatment of rosacea.

While it has long been observed that rosacea may tend to run in families, the first genome-wide association study of rosacea may have discovered the genetic variants that are linked to this chronic skin disorder – as well as potential connections between rosacea and certain autoimmune disorders.¹

It's well known that stress is a top trigger for rosacea flare-ups, but new research may point to the direct effect stress has on the skin.

The facial skin of rosacea sufferers may be more susceptible to irritants due to impaired barrier function, a recent study found, resulting in the dryness experienced by many with the disorder.

The physical mechanisms behind flushing, the lifestyles of Demodex mites and proper skin care were among the rosacea-related topics covered at the recent 72nd annual meeting of the American Academy of Dermatology in Denver.

The National Rosacea Society (NRS) has awarded funding for two new studies in addition to continuing support for five ongoing studies during the year as part of its research grants program to increase knowledge and understanding of the potential causes and other key aspects of rosacea.